C（3〜6か月） 甲状腺ホルモン核受容体βアイソフォーム1と2の欠損マウス。Thra遺伝子のエクソン4と5がlacZ-neoカセットで置換されている。 Ecole Normale Superieure de Lyon・Olivier Chassande、Jacques Samarutらにより開発。ENS ES細胞（129/Sv）を用いて作出。 E. coli Neomycin resistance gene, E. coli beta-galactosidase, mouse Thra genomic DNA Thra gene knockout mice. Exons 5 through 7 were replaced with a lacZ-neo cassette. <a href='https://brc.riken.jp/mus/pcr06182'>Genotyping protocol -PCR-</a> 鈴木　悟 RBRC06182 条件を付加しない。 true No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.) ＴＲβ-/-, 129-Thrb KO ＴＲβ-/-, 129-Thrb KO Necessary documents for ordering:<ol><li>Order form (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx">English</A>)</li><li>Category I MTA: MTA for distribution with RIKEN BRC (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx">English</A>)</li><li>Acceptance of responsibility for living modified organism (<A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx">Japanese</A> / <A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx">English</A>)</li></ol> Fluorescent Proteins/lacZ System 129S2.129(B6)-Thrb<tm1Olc>/Sasu 129S2.129(B6)-Thrb<tm1Olc>/Sasu C (3-6 months) Satoru SUZUKI Homozygote x Homozygote Homozygote x Homozygote ENS [129/Sv] Developed by Olivier Chassande and Jacques Samarut, Ecole Normale Superieure de Lyon. ENS ES cells derived from 129/Sv were used.